During a commercial break, Gary brought in Patrick, a 19-year-old who's suffering from Hodgkin's Disease and who wanted to meet Howard through the Make-A-Wish Foundation. However, Howard told Gary that he should've waited until after the break to bring Patrick in, explaining that he usually likes to meet his guests when his audience does. Gary responded, through his intercom, that there have been times when Howard has wanted his guests to come in while the show was running a commercial, and that was why he instructed Patrick to go into the studio when he did. Howard told Gary, though, that when he wants a guest in early, he always tells him in advance. As their argument was ending, Howard noted that he was watching Gary on his monitor, and that Sal was putting a rubber penis by Gary's face.
Patrick acknowledged that he isn't dying from his bout with Hodgkin's Disease, but that his condition is severe enough to allow him to be a part of the Make-A-Wish Foundation. Patrick went on to say that he was originally diagnosed with non-Hodgkin's Lymphoma, but, after beating it, developed Hodgkin's Disease. Patrick added that he's had 10 rounds of chemotherapy and there's only so much his body can take. Patrick also pointed out, though, that he realizes when he sees other kids in the hospital that his situation could be worse.
Patrick explained that, in order to participate in the Make-A-Wish Foundation, people have to be 18 years old or younger. However, Patrick also reported that, since he made his initial wish – which was a rejected request to visit the Playboy Mansion – when he was 17, he was able to get his second wish, which was to meet Howard. Patrick then admitted that he's used his disease as a way of getting out of traffic tickets, but that it also caused him to drop out of college. Howard responded that Patrick looked like he was in good shape, before commenting that he was hoping for the type of cancer patient Hulk Hogan mentioned in his song, "Hulkster in Heaven."
Howard wondered if Patrick is able to get women, and he replied that he's been in "a slump" since October. However, Patrick claimed that he lost his virginity when he was 16, and that part of the reason he hasn't had sex since last year is because he sometimes doesn't want to be touched by other people. This led Robin to ask Patrick if he pleasures himself, which he said he does. Bob then pointed out that, if Patrick was interested, he was sure Howard could arrange a "date" between him and Tabitha Stevens. After Bob talked about how amazing Tabitha is at performing oral sex, Howard commented that, given her experience with Jeff the Drunk, Bob must've been Brad Pitt to her.
Cathy from the Make-A-Wish Foundation came into the studio, and noted that the idea for the organization started when a dying boy in Arizona wanted to be a police officer, and the people in the town in which he lived organized for it to happen. Howard noted that, if he ran the organization, he'd limit the age to 12 for the kids who can participate in it, noting that, as the kids get to be teenagers, their wishes start getting more perverse. Howard then said that he's been involved in the Make-A-Wish Foundation in the past, and that, during an interview he was doing with Stone Phillips, he had Gary wheel in a sick child from the organization who wanted to meet him. Howard admitted, though, that the plan to come off as caring backfired, and that the piece Stone aired ripped him apart. Howard also reported that he used to visit another sick child during a period of five years, and that he felt "ripped off" when the child survived his illness. Before he left the studio, Howard asked Patrick if he'd be interested in feeling up Robin, which he said he would be. However, Robin responded that option would never be on the table. Artie then signed a bottle of Jack Daniels for Patrick, and Howard pointed out that, if Patrick ever gets "really sick," he'll take him to Scores.